Brain Injury Biomarkers Are Not Dependent on β-amyloid in Normal Elderly

BACKGROUND: The new criteria for preclinical Alzheimer’s Disease (AD) proposed 3 stages: abnormal levels of β-amyloid (stage 1); stage 1 plus evidence of brain injury (stage 2); and stage 2 plus subtle cognitive changes (stage 3). However, a large group of subjects with normal β-amyloid biomarkers h...

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Bibliographic Details
Main Authors: Knopman, David S., Jack, Clifford R., Wiste, Heather J., Weigand, Stephen D., Vemuri, Prashanthi, Lowe, Val J., Kantarci, Kejal, Gunter, Jeffrey L., Senjem, Matthew L., Mielke, Michelle M., Roberts, Rosebud O., Boeve, Bradley F., Petersen, Ronald C.
Format: Artigo
Language:Inglês
Published: 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3660408/
https://ncbi.nlm.nih.gov/pubmed/23424032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.23816
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