Brain Injury Biomarkers Are Not Dependent on β-amyloid in Normal Elderly

BACKGROUND: The new criteria for preclinical Alzheimer’s Disease (AD) proposed 3 stages: abnormal levels of β-amyloid (stage 1); stage 1 plus evidence of brain injury (stage 2); and stage 2 plus subtle cognitive changes (stage 3). However, a large group of subjects with normal β-amyloid biomarkers h...

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Main Authors: Knopman, David S., Jack, Clifford R., Wiste, Heather J., Weigand, Stephen D., Vemuri, Prashanthi, Lowe, Val J., Kantarci, Kejal, Gunter, Jeffrey L., Senjem, Matthew L., Mielke, Michelle M., Roberts, Rosebud O., Boeve, Bradley F., Petersen, Ronald C.
格式: Artigo
語言:Inglês
出版: 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3660408/
https://ncbi.nlm.nih.gov/pubmed/23424032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.23816
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