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IL-10 production by CD4(+) effector T cells: a mechanism for self-regulation

The development of Th1 lymphocytes is essential for cell-mediated immunity and resistance against intracellular pathogens. However, if left unregulated, the same response can cause serious damage to host tissues and lead to mortality. A number of different paracrine regulatory mechanisms involving d...

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Hlavní autoři: Jankovic, Dragana, Kugler, David G., Sher, Alan
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4105209/
https://ncbi.nlm.nih.gov/pubmed/20200511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2010.8
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