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Hydrophobicity and Helicity Regulate the Antifungal Activity of 14-Helical β-Peptides

[Image: see text] Candida albicans is one of the most prevalent fungal pathogens, causing both mucosal candidiasis and invasive candidemia. Antimicrobial peptides (AMPs), part of the human innate immune system, have been shown to exhibit antifungal activity but have not been effective as pharmaceuti...

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Bibliografiske detaljer
Main Authors: Lee, Myung-Ryul, Raman, Namrata, Gellman, Samuel H., Lynn, David M., Palecek, Sean P.
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2014
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4105187/
https://ncbi.nlm.nih.gov/pubmed/24837702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb500203e
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