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Stem cell differentiation as a many-body problem

Stem cell differentiation has been viewed as coming from transitions between attractors on an epigenetic landscape that governs the dynamics of a regulatory network involving many genes. Rigorous definition of such a landscape is made possible by the realization that gene regulation is stochastic, o...

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Detalhes bibliográficos
Main Authors: Zhang, Bin, Wolynes, Peter G.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4104876/
https://ncbi.nlm.nih.gov/pubmed/24946805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1408561111
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