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Cyclophilin A catalyzes proline isomerization by an electrostatic handle mechanism
Proline isomerization is a ubiquitous process that plays a key role in the folding of proteins and in the regulation of their functions. Different families of enzymes, known as “peptidyl-prolyl isomerases” (PPIases), catalyze this reaction, which involves the interconversion between the cis and tran...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4104850/ https://ncbi.nlm.nih.gov/pubmed/24982184 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1404220111 |
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