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Catalysis of cis/trans isomerization in native HIV-1 capsid by human cyclophilin A
Packaging of cyclophilin A (CypA) into HIV-1 virions is essential for efficient replication; however, the reason for this is unknown. Incorporation is mediated through binding to the Gly-89–Pro-90 peptide bond of the N-terminal domain of HIV-1 capsid (CA(N)). Despite the fact that CypA is a peptidyl...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2002
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC122755/ https://ncbi.nlm.nih.gov/pubmed/11929983 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.082100499 |
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