Mcl-1 Dependence Predicts Response to Vorinostat and Gemtuzumab Ozogamicin in Acute Myeloid Leukemia

Older adults with acute myeloid leukemia (AML) are commonly considered for investigational therapies, which often only benefit subsets of patients. In this exploratory, we assessed whether BH3 profiling of apoptotic functionality could predict outcomes following treatment with vorinostat (histone de...

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Huvudupphovsmän: Pierceall, William E., Lena, Ryan J., Medeiros, Bruno C., Blake, Noel, Doykan, Camille, Elaschoff, Michael, Cardone, Michael H., Walter, Roland B.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2014
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4104771/
https://ncbi.nlm.nih.gov/pubmed/24636337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.leukres.2014.02.007
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