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Analysis of the N-terminal Positively Charged Residues of the Simian Immunodeficiency Virus Vif Reveals a Critical Amino Acid Required for the Antagonism of Rhesus APOBEC3D, G, and H

Previous studies have shown that apolipoprotein B mRNA editing, enzyme catalytic, polypeptide G (APOBEC3G; hA3G) and F (APOBEC3F; hA3F) proteins interact with a nonlinear binding site located at the N-terminal region of the HIV-1 Vif protein. We have analyzed the role of 12 positively charged amino...

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Detalhes bibliográficos
Main Authors: Schmitt, Kimberly, Katuwal, Miki, Wang, Yaqiong, Li, Cicy, Stephens, Edward B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4104721/
https://ncbi.nlm.nih.gov/pubmed/24418547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2013.10.037
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