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The reduction of Na/H exchanger-3 protein and transcript expression in acute ischemia–reperfusion injury is mediated by extractable tissue factor(s)

Ischemic renal injury is a formidable clinical problem, the pathophysiology of which is incompletely understood. As the Na/H exchanger-3 (NHE3) mediates the bulk of apical sodium transport and a significant fraction of oxygen consumption in the proximal tubule, we examined mechanisms by which ischem...

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Autori principali: Sole, Francesca Di, Hu, Ming-Chang, Zhang, Jianning, Babich, Victor, Bobulescu, I. Alexandru, Shi, Mingjun, McLeroy, Paul, Rogers, Thomas E., Moe, Orson W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4104484/
https://ncbi.nlm.nih.gov/pubmed/21814178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2011.229
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