Endoplasmic reticulum aminopeptidase-1 alleles associated with increased risk of Ankylosing Spondylitis reduce HLA-B27 mediated presentation of multiple antigens

Ankylosing spondylitis (AS) is a chronic systemic arthritic disease that leads to significant disability and loss of quality of life in the ~0.5% of the worldwide human population it affects. There is currently no cure for AS and mechanisms underlying its pathogenesis remain unclear. AS is highly ge...

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Hauptverfasser: Seregin, Sergey S., Rastall, David P.W., Evnouchidou, Irini, Aylsworth, Charles F., Quiroga, Dionisia, Kamal, Ram P., Godbehere-Roosa, Sarah, Blum, Christopher F., York, Ian A., Stratikos, Efstratios, Amalfitano, Andrea
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4104477/
https://ncbi.nlm.nih.gov/pubmed/24028501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/08916934.2013.819855
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