G1-arrested newborn cells are the predominant infectious form of the pathogen Brucella abortus

Several intracellular pathogens, such as Brucella abortus, display a biphasic infection process starting with a non-proliferative stage of unclear nature. Here, we study the cell cycle of B. abortus at the single-cell level, in culture and during infection of HeLa cells and macrophages. The localiza...

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Autors principals: Deghelt, Michaël, Mullier, Caroline, Sternon, Jean-François, Francis, Nayla, Laloux, Géraldine, Dotreppe, Delphine, Van der Henst, Charles, Jacobs-Wagner, Christine, Letesson, Jean-Jacques, De Bolle, Xavier
Format: Artigo
Idioma:Inglês
Publicat: Nature Pub. Group 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4104442/
https://ncbi.nlm.nih.gov/pubmed/25006695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms5366
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