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Direct Evaluation of tRNA Aminoacylation Status by the T-box Riboswitch Using Intermolecular Stacking and Steric Readout
T-boxes are gene-regulatory mRNA elements with which Gram-positive bacteria sense amino acid availability. T-boxes have two functional domains. Stem I recognizes the overall shape and anticodon of tRNA, while a 3′ domain evaluates its aminoacylation status, overcoming an otherwise stable transcripti...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2014
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4104367/ https://ncbi.nlm.nih.gov/pubmed/24954903 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2014.05.017 |
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