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Synthesis of phospholipids on a glyceric acid scaffold: design and preparation of phospholipase A(2) specific substrates

Synthesis of a new series of phospholipid analogues to serve as activity-based probes of secretory phospholipase A(2) enzymes is reported. The synthesis is based upon 1) preparation of long-chain esters and amides of glyceric acid, followed by 2) regioselective derivatization of the diol function of...

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Detalhes bibliográficos
Main Authors: Rosseto, Renato, Hajdu, Joseph
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4104365/
https://ncbi.nlm.nih.gov/pubmed/25061236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2014.03.054
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