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Synthesis of phospholipids on a glyceric acid scaffold: design and preparation of phospholipase A(2) specific substrates
Synthesis of a new series of phospholipid analogues to serve as activity-based probes of secretory phospholipase A(2) enzymes is reported. The synthesis is based upon 1) preparation of long-chain esters and amides of glyceric acid, followed by 2) regioselective derivatization of the diol function of...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4104365/ https://ncbi.nlm.nih.gov/pubmed/25061236 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2014.03.054 |
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