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Targeted repression of AXIN2 and MYC gene expression using designer TALEs

Designer TALEs (dTALEs) are chimeric transcription factors that can be engineered to regulate gene expression in mammalian cells. Whether dTALEs can block gene transcription downstream of signal transduction cascades, however, has yet to be fully explored. Here we tested whether dTALEs can be used t...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Rennoll, Sherri A., Scott, Samantha A., Yochum, Gregory S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4104357/
https://ncbi.nlm.nih.gov/pubmed/24667606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2014.03.077
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