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Targeted repression of AXIN2 and MYC gene expression using designer TALEs
Designer TALEs (dTALEs) are chimeric transcription factors that can be engineered to regulate gene expression in mammalian cells. Whether dTALEs can block gene transcription downstream of signal transduction cascades, however, has yet to be fully explored. Here we tested whether dTALEs can be used t...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4104357/ https://ncbi.nlm.nih.gov/pubmed/24667606 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2014.03.077 |
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