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Behavioral analysis of male and female Fmr1 knockout mice on C57BL/6 background

Fragile X syndrome (FXS) is a monogenic disease caused by mutations in the FMR1 gene. The Fmr1 knockout (KO) mice show many aspects of FXS-related phenotypes, and have been used as a major pre-clinical model for FXS. Although FXS occurs in both male and female patients, most studies on the mouse mod...

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Autors principals: Ding, Qi, Sethna, Ferzin, Wang, Hongbing
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4104211/
https://ncbi.nlm.nih.gov/pubmed/24886775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbr.2014.05.046
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