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Cytosolic Quality Control of Mislocalized Proteins Requires RNF126 Recruitment to Bag6

Approximately 30% of eukaryotic proteins contain hydrophobic signals for localization to the secretory pathway. These proteins can be mislocalized in the cytosol due to mutations in their targeting signals, certain stresses, or intrinsic inefficiencies in their translocation. Mislocalized proteins (...

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Bibliografische gegevens
Hoofdauteurs: Rodrigo-Brenni, Monica C., Gutierrez, Erik, Hegde, Ramanujan S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cell Press 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4104027/
https://ncbi.nlm.nih.gov/pubmed/24981174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2014.05.025
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