Sharpening of expression domains induced by transcription and microRNA regulation within a spatio-temporal model of mid-hindbrain boundary formation

BACKGROUND: The establishment of the mid-hindbrain region in vertebrates is mediated by the isthmic organizer, an embryonic secondary organizer characterized by a well-defined pattern of locally restricted gene expression domains with sharply delimited boundaries. While the function of the isthmic o...

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Autori principali: Hock, Sabrina, Ng, Yen-Kar, Hasenauer, Jan, Wittmann, Dominik, Lutter, Dominik, Trümbach, Dietrich, Wurst, Wolfgang, Prakash, Nilima, Theis, Fabian J
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4103684/
https://ncbi.nlm.nih.gov/pubmed/23799959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-7-48
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