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Noise drives sharpening of gene expression boundaries in the zebrafish hindbrain

Morphogens provide positional information for spatial patterns of gene expression during development. However, stochastic effects such as local fluctuations in morphogen concentration and noise in signal transduction make it difficult for cells to respond to their positions accurately enough to gene...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Zhang, Lei, Radtke, Kelly, Zheng, Likun, Cai, Anna Q, Schilling, Thomas F, Nie, Qing
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3472692/
https://ncbi.nlm.nih.gov/pubmed/23010996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2012.45
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