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A change-point model for identifying 3′UTR switching by next-generation RNA sequencing

Motivation: Next-generation RNA sequencing offers an opportunity to investigate transcriptome in an unprecedented scale. Recent studies have revealed widespread alternative polyadenylation (polyA) in eukaryotes, leading to various mRNA isoforms differing in their 3′ untranslated regions (3′UTR), thr...

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Detalles Bibliográficos
Main Authors: Wang, Wei, Wei, Zhi, Li, Hongzhe
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2014
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4103598/
https://ncbi.nlm.nih.gov/pubmed/24728858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btu189
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