MicroRNAs targeting Nicastrin regulate Aβ production and are affected by target site polymorphisms

Despite the growing number of genome-wide association studies, the involvement of polymorphisms in microRNA target sites (polymiRTS) in Alzheimer’s disease (AD) remains poorly investigated. Recently, we have shown that AD-associated single-nucleotide polymorphisms (SNPs) present in the 3′ untranslat...

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Bibliografiske detaljer
Main Authors: Delay, Charlotte, Dorval, Véronique, Fok, Alice, Grenier-Boley, Benjamin, Lambert, Jean-Charles, Hsiung, G.-Y., Hébert, Sébastien S.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2014
Fag:
Neuroscience
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4103510/
https://ncbi.nlm.nih.gov/pubmed/25100943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2014.00067
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