Actin-binding protein 1 links B-cell antigen receptors to negative signaling pathways

Prolonged or uncontrolled B-cell receptor (BCR) signaling is associated with autoimmunity. We previously demonstrated a role for actin in BCR signal attenuation. This study reveals that actin-binding protein 1 (Abp1/HIP-55/SH3P7) is a negative regulator of BCR signaling and links actin to negative r...

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Detalhes bibliográficos
Main Authors: Seeley-Fallen, Margaret K., Liu, Lisa J., Shapiro, Melanie R., Onabajo, Olusegun O., Palaniyandi, Senthilkumar, Zhu, Xiaoping, Tan, Tse-Hua, Upadhyaya, Arpita, Song, Wenxia
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4103327/
https://ncbi.nlm.nih.gov/pubmed/24958882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1321971111
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