Increased vesicular monoamine transporter enhances dopamine release and opposes Parkinson disease-related neurodegeneration in vivo

Disruption of neurotransmitter vesicle dynamics (transport, capacity, release) has been implicated in a variety of neurodegenerative and neuropsychiatric conditions. Here, we report a novel mouse model of enhanced vesicular function via bacterial artificial chromosome (BAC)-mediated overexpression o...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Lohr, Kelly M., Bernstein, Alison I., Stout, Kristen A., Dunn, Amy R., Lazo, Carlos R., Alter, Shawn P., Wang, Minzheng, Li, Yingjie, Fan, Xueliang, Hess, Ellen J., Yi, Hong, Vecchio, Laura M., Goldstein, David S., Guillot, Thomas S., Salahpour, Ali, Miller, Gary W.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: National Academy of Sciences 2014
Θέματα:
Biological Sciences
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4103325/
https://ncbi.nlm.nih.gov/pubmed/24979780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1402134111
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