Increased Vesicular Monoamine Transporter 2 (VMAT2; Slc18a2) Protects against Methamphetamine Toxicity

The psychostimulant methamphetamine (METH) is highly addictive and neurotoxic to dopamine terminals. METH toxicity has been suggested to be due to the release and accumulation of dopamine in the cytosol of these terminals. The vesicular monoamine transporter 2 (VMAT2; SLC18A2) is a critical mediator...

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Pubblicato in:ACS Chem Neurosci
Autori principali: Lohr, Kelly M., Stout, Kristen A., Dunn, Amy R., Wang, Minzheng, Salahpour, Ali, Guillot, Thomas S., Miller, Gary W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4489556/
https://ncbi.nlm.nih.gov/pubmed/25746685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.5b00010
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