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Structural dynamic analysis of apo and ATP-bound IRAK4 kinase
Interleukin-1 receptor-associated kinases (IRAKs) are Ser/Thr protein kinases that play an important role as signaling mediators in the signal transduction facilitated by the Toll-like receptor (TLR) and interleukin-1 receptor families. Among IRAK family members, IRAK4 is one of the drug targets for...
Uloženo v:
| Hlavní autoři: | , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group
2014
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4103033/ https://ncbi.nlm.nih.gov/pubmed/25034608 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep05748 |
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