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Simultaneous Determination of All Forms of Biopterin and Neopterin in Cerebrospinal Fluid

[Image: see text] In humans, genetic defects of the synthesis or regeneration of tetrahydrobiopterin (BH4), an essential cofactor in hydroxylation reactions, are associated with severe neurological disorders. The diagnosis of these conditions relies on the determination of BH4, dihydrobiopterin (BH2...

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Main Authors: Guibal, Pierre, Lévêque, Nathalie, Doummar, Diane, Giraud, Nicolas, Roze, Emmanuel, Rodriguez, Diana, Couderc, Rémy, Billette De Villemeur, Thierry, Moussa, Fathi
Formato: Artigo
Idioma:Inglês
Publicado: American Chemical Society 2014
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4102970/
https://ncbi.nlm.nih.gov/pubmed/24650440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn4001928
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