Correlation of BRAF and NRAS mutation status with outcome, site of distant metastasis and response to chemotherapy in metastatic melanoma

BACKGROUND: The prognostic significance of BRAF and NRAS mutations in metastatic melanoma patients remains uncertain, with several studies reporting conflicting results, often biased by the inclusion of patients treated with BRAF and MEK (MAPK) inhibitors. We therefore interrogated a historical coho...

詳細記述

保存先:
書誌詳細
主要な著者: Carlino, M S, Haydu, L E, Kakavand, H, Menzies, A M, Hamilton, A L, Yu, B, Ng, C C, Cooper, W A, Thompson, J F, Kefford, R F, O'Toole, S A, Scolyer, R A, Long, G V
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2014
主題:
Translational Therapeutics
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4102942/
https://ncbi.nlm.nih.gov/pubmed/24918823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2014.287
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