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Targeted diphtheria toxin to treat BPDCN
In this issue of Blood, Frankel et al describe a novel treatment of blastic plasmacytoid dendritic cell neoplasm (BPDCN) using an engineered version of diphtheria toxin that is targeted to malignant cells via a fusion with interleukin (IL)3 (see panel A).(1)
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| Hovedforfatter: | |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society of Hematology
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4102704/ https://ncbi.nlm.nih.gov/pubmed/25035145 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-06-578633 |
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