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Preclinical and Clinical Evaluation of Forodesine in Pediatric and Adult B-Cell Acute Lymphoblastic Leukemia

Forodesine was originally developed for T-cell leukemias and was effective in T-cell acute lymphoblastic leukemia (T-ALL). The current study was done to test its utility in B-cell ALL (B-ALL). Our preclinical investigations (lymphoblasts from pediatric patients with B-ALL [n=12]) demonstrate activit...

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Détails bibliographiques
Auteurs principaux: Balakrishnan, Kumudha, Ravandi, Farhad, Bantia, Shanta, Franklin, Anna, Gandhi, Varsha
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4102435/
https://ncbi.nlm.nih.gov/pubmed/23773454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clml.2013.04.009
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