Modeling Bi-modality Improves Characterization of Cell Cycle on Gene Expression in Single Cells

Advances in high-throughput, single cell gene expression are allowing interrogation of cell heterogeneity. However, there is concern that the cell cycle phase of a cell might bias characterizations of gene expression at the single-cell level. We assess the effect of cell cycle phase on gene expressi...

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Bibliografiske detaljer
Main Authors: McDavid, Andrew, Dennis, Lucas, Danaher, Patrick, Finak, Greg, Krouse, Michael, Wang, Alice, Webster, Philippa, Beechem, Joseph, Gottardo, Raphael
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4102402/
https://ncbi.nlm.nih.gov/pubmed/25032992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003696
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