Regulation of Intrinsic Axon Growth Ability at Retinal Ganglion Cell Growth Cones

PURPOSE. Mammalian central nervous system neurons fail to regenerate after injury or disease, in part due to a progressive loss in intrinsic axon growth ability after birth. Whether lost axon growth ability is due to limited growth resources or to changes in the axonal growth cone is unknown. METHOD...

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Main Authors: Steketee, Michael B., Oboudiyat, Carly, Daneman, Richard, Trakhtenberg, Ephraim, Lamoureux, Philip, Weinstein, Jessica E., Heidemann, Steve, Barres, Ben A., Goldberg, Jeffrey L.
Format: Artigo
Sprog:Inglês
Udgivet: The Association for Research in Vision and Ophthalmology 2014
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4102390/
https://ncbi.nlm.nih.gov/pubmed/24906860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.14-13882
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