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von Willebrand factor: an emerging target in stroke therapy

Thrombus formation is of paramount importance in the pathophysiology of acute ischemic stroke. Current antithrombotics used to treat or prevent cerebral ischemia are only moderately effective or bear an increased risk of severe bleeding. von Willebrand factor (VWF) has long been known to be a key pl...

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Detalhes bibliográficos
Main Authors: De Meyer, Simon F., Stoll, Guido, Wagner, Denisa D., Kleinschnitz, Christoph
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4102321/
https://ncbi.nlm.nih.gov/pubmed/22180250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.111.628867
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