Osteoponin Promoter Controlled by DNA Methylation: Aberrant Methylation in Cloned Porcine Genome

Cloned animals usually exhibited many defects in physical characteristics or aberrant epigenetic reprogramming, especially in some important organ development. Osteoponin (OPN) is an extracellular-matrix protein involved in heart and bone development and diseases. In this study, we investigated the...

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Autores principales: Shen, Chih-Jie, Tsou, Yung-An, Chen, Hsiao-Ling, Huang, Hung-Jin, Wu, Shinn-Chih, Cheng, Winston T. K., Chen, Calvin Yu-Chian, Chen, Chuan-Mu
Formato: Artigo
Lenguaje:Inglês
Publicado: Hindawi Publishing Corporation 2014
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4102072/
https://ncbi.nlm.nih.gov/pubmed/25101273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/327538
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