Differential Differences in Methylation Status of Putative Imprinted Genes among Cloned Swine Genomes

DNA methylation is a major epigenetic modification in the mammalian genome that regulates crucial aspects of gene function. Mammalian cloning by somatic cell nuclear transfer (SCNT) often results in gestational or neonatal failure with only a small proportion of manipulated embryos producing live bi...

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Bibliographische Detailangaben
Hauptverfasser: Shen, Chih-Jie, Cheng, Winston T. K., Wu, Shinn-Chih, Chen, Hsiao-Ling, Tsai, Tung-Chou, Yang, Shang-Hsun, Chen, Chuan-Mu
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3290620/
https://ncbi.nlm.nih.gov/pubmed/22393450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032812
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