ADAMTS4 and ADAMTS5 Knockout Mice Are Protected from Versican but Not Aggrecan or Brevican Proteolysis during Spinal Cord Injury

The chondroitin sulfate proteoglycans (CSPGs) aggrecan, versican, and brevican are large aggregating extracellular matrix molecules that inhibit axonal growth of the mature central nervous system (CNS). ADAMTS proteoglycanases, including ADAMTS4 and ADAMTS5, degrade CSPGs, representing potential tar...

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Detalhes bibliográficos
Main Authors: Demircan, Kadir, Topcu, Vehap, Takigawa, Tomoyuki, Akyol, Sumeyya, Yonezawa, Tomoko, Ozturk, Gulfer, Ugurcu, Veli, Hasgul, Rukiye, Yigitoglu, M. Ramazan, Akyol, Omer, McCulloch, Daniel R., Hirohata, Satoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4101972/
https://ncbi.nlm.nih.gov/pubmed/25101296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/693746
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