ADAMTS4 and ADAMTS5 Knockout Mice Are Protected from Versican but Not Aggrecan or Brevican Proteolysis during Spinal Cord Injury

The chondroitin sulfate proteoglycans (CSPGs) aggrecan, versican, and brevican are large aggregating extracellular matrix molecules that inhibit axonal growth of the mature central nervous system (CNS). ADAMTS proteoglycanases, including ADAMTS4 and ADAMTS5, degrade CSPGs, representing potential tar...

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Bibliografiske detaljer
Main Authors: Demircan, Kadir, Topcu, Vehap, Takigawa, Tomoyuki, Akyol, Sumeyya, Yonezawa, Tomoko, Ozturk, Gulfer, Ugurcu, Veli, Hasgul, Rukiye, Yigitoglu, M. Ramazan, Akyol, Omer, McCulloch, Daniel R., Hirohata, Satoshi
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4101972/
https://ncbi.nlm.nih.gov/pubmed/25101296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/693746
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