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Aromatic-L-amino-acid decarboxylase, a pyridoxal phosphate-dependent enzyme, is a beta-cell autoantigen.

Different autoantigens are thought to be involved in the pathogenesis of insulin-dependent diabetes mellitus, and they may account for the variation in the clinical presentation of the disease. Sera from patients with autoimmune polyendocrine syndrome type I contain autoantibodies against the beta-c...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Principais autores: Rorsman, F, Husebye, E S, Winqvist, O, Björk, E, Karlsson, F A, Kämpe, O
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 1995
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41019/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7567987/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.19.8626
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