Aromatic-L-amino-acid decarboxylase, a pyridoxal phosphate-dependent enzyme, is a beta-cell autoantigen.

Different autoantigens are thought to be involved in the pathogenesis of insulin-dependent diabetes mellitus, and they may account for the variation in the clinical presentation of the disease. Sera from patients with autoimmune polyendocrine syndrome type I contain autoantibodies against the beta-c...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Rorsman, F, Husebye, E S, Winqvist, O, Björk, E, Karlsson, F A, Kämpe, O
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41019/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7567987/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.19.8626
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