Large T Antigen-Specific Cytotoxic T Cells Protect Against Dendritic Cell Tumors through Perforin-Mediated Mechanisms Independent of CD4 T Cell Help

Our newly generated murine tumor dendritic cell (MuTuDC) lines, generated from tumors developing in transgenic mice expressing the simian virus 40 large T antigen (SV40LgT) and GFP under the DC specific promoter CD11c, reproduce the phenotypic and functional properties of splenic wild type CD8α(+) c...

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Bibliografiska uppgifter
Huvudupphovsmän: Duval, Anaïs, Fuertes Marraco, Silvia A., Schwitter, Dominik, Leuenberger, Line, Acha-Orbea, Hans
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2014
Ämnen:
Immunology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4101877/
https://ncbi.nlm.nih.gov/pubmed/25101081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2014.00338
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