Large T Antigen-Specific Cytotoxic T Cells Protect Against Dendritic Cell Tumors through Perforin-Mediated Mechanisms Independent of CD4 T Cell Help

Our newly generated murine tumor dendritic cell (MuTuDC) lines, generated from tumors developing in transgenic mice expressing the simian virus 40 large T antigen (SV40LgT) and GFP under the DC specific promoter CD11c, reproduce the phenotypic and functional properties of splenic wild type CD8α(+) c...

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Detalles Bibliográficos
Main Authors: Duval, Anaïs, Fuertes Marraco, Silvia A., Schwitter, Dominik, Leuenberger, Line, Acha-Orbea, Hans
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2014
Assuntos:
Immunology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4101877/
https://ncbi.nlm.nih.gov/pubmed/25101081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2014.00338
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