Modulation by metformin of molecular and histopathological alterations in the lung of cigarette smoke-exposed mice

The anti-diabetic drug metformin is endowed with anti-cancer properties. Epidemiological and experimental studies, however, did not provide univocal results regarding its role in pulmonary carcinogenesis. We used Swiss H mice of both genders in order to detect early molecular alterations and tumors...

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Bibliographische Detailangaben
Hauptverfasser: Izzotti, Alberto, Balansky, Roumen, D'Agostini, Francesco, Longobardi, Mariagrazia, Cartiglia, Cristina, Micale, Rosanna T, La Maestra, Sebastiano, Camoirano, Anna, Ganchev, Gancho, Iltcheva, Marietta, Steele, Vernon E, De Flora, Silvio
Format: Artigo
Sprache:Inglês
Veröffentlicht: BlackWell Publishing Ltd 2014
Schlagworte:
Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4101764/
https://ncbi.nlm.nih.gov/pubmed/24683044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.234
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