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The Ca(2+)-activated Cl(−) channel, ANO1 (TMEM16A), is a double-edged sword in cell proliferation and tumorigenesis
Since anoctamin 1 ANO1 (TMEM16A) was found to be a molecular component of Ca(2+)-activated Cl(−) channels, its role in tumorigenesis has gained attention at a fast pace. ANO1 overexpression frequently occurs in the cancer tissues along with 11q13 chromosome amplification. Poor prognosis of many type...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BlackWell Publishing Ltd
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4101736/ https://ncbi.nlm.nih.gov/pubmed/24639373 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.232 |
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