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Epigenetic silencing of genes and microRNAs within the imprinted Dlk1-Dio3 region at human chromosome 14.32 in giant cell tumor of bone

BACKGROUND: Growing evidence exists that the neoplastic stromal cell population (GCTSC) within giant cell tumors (GCT) originates from mesenchymal stem cells (MSC). In a previous study we identified a microRNA signature that differentiates between these cell types. Five differentially expressed micr...

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Autori principali: Lehner, Burkhard, Kunz, Pierre, Saehr, Heiner, Fellenberg, Joerg
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4101709/
https://ncbi.nlm.nih.gov/pubmed/25005035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-495
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