Patterns of Molecular Response to and Relapse After Combination of Sorafenib, Idarubicin, and Cytarabine in Patients With FLT3 Mutant Acute Myeloid Leukemia

BACKGROUND: FMS-like tyrosine kinase 3 (FLT3) is a class III receptor tyrosine kinase involved in hematopoietic progenitor cell development. Mutations of FLT3 have been reported in about a third of patients with acute myeloid leukemia (AML), and inhibitors of FLT3 are of clinical interest. Sorafenib...

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Главные авторы: Al-Kali, Aref, Cortes, Jorge, Faderl, Stefan, Jones, Dan, Abril, Caroline, Pierce, Sherry, Brandt, Mark, Kantarjian, Hagop, Ravandi, Farhad
Формат: Artigo
Язык:Inglês
Опубликовано: 2011
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4101692/
https://ncbi.nlm.nih.gov/pubmed/21816375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clml.2011.06.007
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