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Loss of lamin B1 results in prolongation of S phase and decondensation of chromosome territories
Nuclear lamin B1 (LMNB1) constitutes one of the major structural proteins in the lamina mesh. We silenced the expression of LMNB1 by RNA interference in the colon cancer cell line DLD-1 and showed a dramatic redistribution of H3K27me3 from the periphery to a more homogeneous nuclear dispersion. In a...
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| Autores principales: | , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Federation of American Societies for Experimental Biology
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4101663/ https://ncbi.nlm.nih.gov/pubmed/24732130 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.14-250456 |
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