Loss of lamin B1 results in prolongation of S phase and decondensation of chromosome territories

Nuclear lamin B1 (LMNB1) constitutes one of the major structural proteins in the lamina mesh. We silenced the expression of LMNB1 by RNA interference in the colon cancer cell line DLD-1 and showed a dramatic redistribution of H3K27me3 from the periphery to a more homogeneous nuclear dispersion. In a...

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Bibliografiske detaljer
Main Authors: Camps, Jordi, Wangsa, Darawalee, Falke, Martin, Brown, Markus, Case, Chanelle M., Erdos, Michael R., Ried, Thomas
Format: Artigo
Sprog:Inglês
Udgivet: Federation of American Societies for Experimental Biology 2014
Fag:
Research Communications
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4101663/
https://ncbi.nlm.nih.gov/pubmed/24732130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.14-250456
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