Epigenetic regulation of aortic remodeling in hyperhomocysteinemia

Hyperhomocysteinemia (HHcy) is prevalent in patients with hypertension and is an independent risk factor for aortic pathologies. HHcy is known to cause an imbalance between matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs), leading to the accumulation of collagen i...

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Detalhes bibliográficos
Main Authors: Narayanan, Nithya, Pushpakumar, Sathnur Basappa, Givvimani, Srikanth, Kundu, Sourav, Metreveli, Naira, James, Dexter, Bratcher, Adrienne P., Tyagi, Suresh C.
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2014
Assuntos:
Research Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4101656/
https://ncbi.nlm.nih.gov/pubmed/24739303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.14-250183
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