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Embryo number and periconceptional undernutrition in the sheep have differential effects on adrenal epigenotype, growth, and development

Exposure to poor maternal nutrition around the time of conception results in an early prepartum activation of the fetal pituitary-adrenal axis and in increased adrenal growth and stress response after birth associated with epigenetic changes in a differentially methylated region (DMR) of adrenal IGF...

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Hlavní autoři: Williams-Wyss, Olivia, Zhang, Song, MacLaughlin, Severence M., Kleemann, David, Walker, Simon K., Suter, Catherine M., Cropley, Jennifer E., Morrison, Janna L., Roberts, Claire T., Caroline McMillen, I.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4101636/
https://ncbi.nlm.nih.gov/pubmed/24844259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00051.2012
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