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Impairments of hepatic gluconeogenesis and ketogenesis in PPARα-deficient neonatal mice
Peroxisome proliferator activated receptor-α (PPARα) is a master transcriptional regulator of hepatic metabolism and mediates the adaptive response to fasting. Here, we demonstrate the roles for PPARα in hepatic metabolic adaptations to birth. Like fasting, nutrient supply is abruptly altered at bir...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Physiological Society
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4101633/ https://ncbi.nlm.nih.gov/pubmed/24865983 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00087.2014 |
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