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Use of LC-MS/MS and Bayes' theorem to identify protein kinases that phosphorylate aquaporin-2 at Ser(256)

In the renal collecting duct, binding of AVP to the V(2) receptor triggers signaling changes that regulate osmotic water transport. Short-term regulation of water transport is dependent on vasopressin-induced phosphorylation of aquaporin-2 (AQP2) at Ser(256). The protein kinase that phosphorylates t...

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Autori principali: Bradford, Davis, Raghuram, Viswanathan, Wilson, Justin L. L., Chou, Chung-Lin, Hoffert, Jason D., Knepper, Mark A., Pisitkun, Trairak
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4101623/
https://ncbi.nlm.nih.gov/pubmed/24598363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00377.2012
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