Comprehensive database of human E3 ubiquitin ligases: application to aquaporin-2 regulation

Aquaporin-2 (AQP2) is regulated in part via vasopressin-mediated changes in protein half-life that are in turn dependent on AQP2 ubiquitination. Here we addressed the question, “What E3 ubiquitin ligase is most likely to be responsible for AQP2 ubiquitination?” using large-scale data integration bas...

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Bibliografske podrobnosti
izdano v:Physiol Genomics
Main Authors: Medvar, Barbara, Raghuram, Viswanathan, Pisitkun, Trairak, Sarkar, Abhijit, Knepper, Mark A.
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2016
Teme:
General Interest
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4967219/
https://ncbi.nlm.nih.gov/pubmed/27199454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00031.2016
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