UCP2 mediates ghrelin's action on NPY/AgRP neurons by lowering free radicals

The gut-derived hormone ghrelin exerts its effect on the brain by regulating neuronal activity. Ghrelin-induced feeding behaviour is controlled by arcuate nucleus neurons that co-express neuropeptide Y and agouti-related protein (NPY/AgRP neurons). However, the intracellular mechanisms triggered by...

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Hauptverfasser: Andrews, Zane B., Liu, Zhong-Wu, Walllingford, Nicholas, Erion, Derek M., Borok, Erzsebet, Friedman, Jeffery M., Tschöp, Matthias H., Shanabrough, Marya, Cline, Gary, Shulman, Gerald I., Coppola, Anna, Gao, Xiao-Bing, Horvath, Tamas L., Diano, Sabrina
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4101536/
https://ncbi.nlm.nih.gov/pubmed/18668043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07181
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